Idiopathic thrombocytopenic purpura, Helicobacter pylori infection, and HLA class II alleles.
نویسندگان
چکیده
care is taken to inhibit ex vivo enzyme activity.4 We sent a blinded set of our samples to Dr Asselin, and she confirmed the asparagine values we reported. Liver perfusion studies and modeling of asparaginase treatment suggest that there is a high rate of asparagine input into the circulation from diet and the tissues.5,6 An equilibrium between the rate of asparagine input and the asparaginase activity can result in a low (nonzero) steady-state asparagine concentration.
منابع مشابه
Idiopathic thrombocytopenic purpura, Helicobacter pylori infection, and HLA class II alleles
care is taken to inhibit ex vivo enzyme activity.4 We sent a blinded set of our samples to Dr Asselin, and she confirmed the asparagine values we reported. Liver perfusion studies and modeling of asparaginase treatment suggest that there is a high rate of asparagine input into the circulation from diet and the tissues.5,6 An equilibrium between the rate of asparagine input and the asparaginase ...
متن کاملHelicobacter pylori and idiopathic thrombocytopenic purpura in children.
Helicobacter pylori gastritis has been associated with autoimmune diseases, including idiopathic thrombocytopenic purpura (ITP).1,2 It is well known that the prevalence of H pylori infection is greatly variable from country to country, has decreased over the last decades in industrialized countries, and that its frequency increases with age. Recently, Veneri et al3 suggested that the HLA class ...
متن کاملTo the editor: Helicobacter pylori and idiopathic thrombocytopenic purpura in children
Helicobacter pylori gastritis has been associated with autoimmune diseases, including idiopathic thrombocytopenic purpura (ITP).1,2 It is well known that the prevalence of H pylori infection is greatly variable from country to country, has decreased over the last decades in industrialized countries, and that its frequency increases with age. Recently, Veneri et al3 suggested that the HLA class ...
متن کاملHelicobacter pylori Eradication in Adult Patients with Acute Idiopathic Thrombocytopenic Purpura (ITP)
Background and Objective: Different studies have investigated the link between helicobacter pylori and extra digestive diseases such as idiopathic thrombocytopenic purpura. However, the relationship between ITP and H pylori is less clear. Most of the studies have focused on H pylori eradication in chronic ITP, so we focused on the effect of H pylori eradication on chronicity of ITP in adult pat...
متن کاملEffects of a Helicobacter pylori eradication regimen on anti-platelet autoantibody response in infected and uninfected patients with idiopathic thrombocytopenic purpura.
Thirty-seven patients with idiopathic thrombocytopenic purpura (ITP) were treated with a standard Helicobacter pylori eradication regimen irrespective of H. pylori infection. Our results indicate that platelet recovery results from the disappearance of H. pylori itself, and is mediated, in part, through suppression of anti-platelet autoantibody production.
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ورودعنوان ژورنال:
- Blood
دوره 100 5 شماره
صفحات -
تاریخ انتشار 2002